Uncategorized

Bassil Dahiyat, Ph.D., CEO of Xencor and biotech industry leader, joins the Board of Directors

Pasadena, Calif., November 30, 2022 – Terray Therapeutics, a biotechnology company accelerating drug discovery through the application of computational approaches to precisely generated chemical data at scale, today announced the appointment of Bassil Dahiyat, Ph.D., as an Independent Director.

“We are incredibly fortunate to have Bassil join the Terray team,” said Jacob Berlin, Ph.D., Chief Executive Officer of Terray. “He is a true biotech pioneer who has shifted the paradigm in protein engineering. His deep experience in both the field and in company building will be invaluable to Terray during this period of growth.”

Bassil Dahiyat has been Xencor’s president and chief executive officer since the Company’s incorporation in August 1997, and is the co-founder of Xencor, and co-inventor of Xencor’s breakthrough XmAb® technology. He has led the Company in creating a diverse clinical-stage portfolio of engineered antibodies and cytokines for the treatment of life-threatening and debilitating diseases, and has established alliances with leading biopharmaceutical companies that have resulted in three marketed drugs. Dr. Dahiyat has co-authored numerous scientific papers in the fields of protein design and drug delivery, is an inventor of over 30 U.S. and numerous foreign patents and has received scientific awards from the American Chemical Society, the Controlled Release Society, the Protein Society and Caltech. Dr. Dahiyat also serves as a member of the board of directors of Kodiak Sciences, a publicly traded biopharmaceutical company. He holds a Ph.D. in Chemistry from Caltech and B.S. and M.S.E. degrees in Biomedical Engineering from the Johns Hopkins University.

“I am thrilled to join the Terray Board of Directors and work with the talented team of scientists they have assembled,” said Dr. Dahiyat. “Drug discovery has long been constrained by challenges in scale and resources. Terray’s novel platform can overcome these barriers by combining massively scaled experimental screening and advanced computation to discover drug candidates that expand what’s possible for new therapeutics and for patients.”

# # #

About Terray Therapeutics

Terray Therapeutics is a biotechnology company operating at the convergence of AI, biology, medicinal chemistry, automation, and nanotechnology to propel drug discovery into the information age. Terray’s proprietary integrated computational and experimental platforms generate massively scaled, powerfully agnostic chemical data that are purpose-built to power computational learning and reveal new interactions. This foundation is building an iterative, flexible chemistry engine that delivers more precise therapies to patients faster than ever before. To learn more about Terray, visit terraytx.com.

Media Contact

Peg Rusconi, Verge Scientific: prusconi@vergescientific.com

Collaboration combines Calico’s deep expertise in target biology with Terray’s proprietary drug discovery and development platform to identify novel therapeutics for patients affected by serious diseases of aging, including cancer

PASADENA, Calif. and SOUTH SAN FRANCISCO, Calif., October 12, 2022 – Terray Therapeutics, a biotechnology company accelerating drug discovery through the application of computational approaches to precisely generated chemical data at scale; and Calico Life Sciences, a biotechnology organization focused on age-related interventions and founded by Alphabet and Arthur D. Levinson, today announced a research collaboration to discover and develop small molecule therapeutics for diseases of aging, including cancer. 

Under the terms of the agreement, Terray and Calico will identify small molecule leads against a set of targets nominated by Calico using the Terray tNova platform, with Calico subsequently assuming responsibility for development and commercialization. Terray will receive an upfront payment and is eligible to receive milestones as well as tiered royalties on net sales.

“We are thrilled to collaborate with Calico and look forward to applying our discovery engine to identify modulators of previously intractable disease targets,” said Jacob Berlin, Ph.D., Chief Executive Officer of Terray. “Our combined expertise will leverage the scale, precision, and speed of our tNova platform to rapidly discover and advance therapeutics for patients.”

Chemical datasets generated using Terray’s novel ultra-dense microarray technology are analyzed with Terray’s integrated machine learning and computational platform to systemically map biochemical interactions between small molecules and disease targets. Terray’s chemistry engine operates at a massive scale, measuring billions of interactions daily and becoming increasingly precise with each cycle of design and experimentation. Combining these capabilities with wet lab and computationally-driven drug development workflows, Terray enables and accelerates small molecule drug discovery across a wide variety of targets.

“Terray’s platform offers a new opportunity to more precisely assess the biochemical dynamics between disease targets and small molecules at a very large scale,” said Jonathan W. Lewis, Ph.D., Chief Business Officer at Calico. “We look forward to partnering with the team at Terray to jointly discover first-in-class therapeutics against age-related diseases.”

About Calico

Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. To learn more about Calico, visit www.calicolabs.com.

About Terray Therapeutics

Terray Therapeutics is a biotechnology company operating at the convergence of AI, biology, medicinal chemistry, automation, and nanotechnology to propel drug discovery into the information age. Terray’s proprietary integrated computational and experimental platforms generate massively scaled, powerfully agnostic chemical data that are purpose-built to power computational learning and reveal new interactions. This foundation is building an iterative, flexible chemistry engine that delivers more precise therapies to patients faster than ever before. To learn more about Terray, visit terraytx.com.

###

Terray Therapeutics Media Contact
Peg Rusconi, Verge Scientific: prusconi@vergescientific.com

Calico Media Contact
Minna Kane, mkane@calicolabs.com

Fiona Black, PhD to join Terray’s Scientific Advisory Board

PASADENA, Cali., July 12, 2022 – Terray Therapeutics, a biotechnology company propelling drug discovery into the information age, today announced the appointment of Fiona Black, PhD to its Scientific Advisory Board, adding valuable expertise in interdisciplinary technology development of both market-leading, end-to-end product solutions and operationally efficient and scalable manufacturing processes.

“We are thrilled to welcome Dr. Black to our Scientific Advisory Board,” said Chief Executive Officer Jacob Berlin, PhD. “Fiona’s work integrating diverse fields of science and engineering, for things such as polymeric drug delivery systems and rapid, low-cost biochemical ligand detection, will further support Terray’s mission to bridge the gap between discovery and treatment for patients.”

Dr. Fiona Black has more than 20 years of notable experience at leading biotechnology and biomedical organizations. Most recently, Fiona led Illumina’s Array portfolio R&D organization. Fiona has a Ph.D. in Biophysics and Surface Chemistry from the University of Nottingham, U.K., and a Bachelor of Sciences, with first-class honors, in Medical and Pharmaceutical Chemistry from Loughborough University, U.K. 

“I am very impressed with the expertise of the team and the work they are doing here at Terray,” said Dr. Black. “The ability to measure precise chemical-biological interaction data at scale addresses a longstanding pain point in drug discovery.  This, combined with a machine learning approach, provides exponential potential to transform the field. I am delighted to join the Scientific Advisory Board at this pivotal stage for the company.”

In addition to hiring in key leadership and strategic functions, Terray Therapeutics continues to build on the momentum of their recent $60 million Series A financing by expanding their operational and laboratory capabilities in a new facility in Greater Los Angeles. The company’s new headquarters will occupy nearly 50,000 square feet of combined lab/office space at the Monrovia Technology Campus. This is a significant expansion in footprint and will enable the company to support their next phase of growth.  

About Terray Therapeutics

Terray Therapeutics is an emerging biotechnology company led by pioneers and long-time leaders in AI, medicinal chemistry, biology and preclinical development, automation, and nanotechnology to propel drug discovery into the information age. Terray’s proprietary integrated computational and experimental platforms generate massively scaled, powerfully agnostic chemical data that are purpose-built to power computational learning and reveal new interactions. This foundation is building an iterative, flexible chemistry engine that aims to deliver more precise therapies to patients faster than ever before. Visit terraytx.com to learn more.

Media Contact:

Darby Pearson
dpearson@vergescientific.com

New appointment adds deep expertise in small molecule drug discovery, business development, and strategic partnerships

Dr. Ujjainwalla joins an executive team of pioneers and long-time leaders in artificial intelligence, biology and preclinical development, automation, and nanotechnology

PASADENA, Cali., March 1, 2022 – Terray Therapeutics, a biotechnology company propelling drug discovery into the information age, today announced the appointment of Feroze (Fez) Ujjainwalla, PhD, as Head of Business. He joins an expanding lineup of industry veterans including Vanessa Taylor, Terray’s Head of Biology and Preclinical Development, Narbe Mardirossian, Terray’s Head of Computational and Data Science and Craig Schulz, Terray’s Head of Automation. The combined expertise of the executive team will advance Terray’s mission to deliver premium chemical data at unrivaled scale, unlocking the potential of AI-driven small molecule drug discovery.

“We are thrilled to welcome Fez to the team as we start this new chapter in the Terray story,” said Chief Executive Officer Jacob Berlin, PhD. “Fez brings over 20 years of drug discovery and development experience to our interdisciplinary team of highly skilled computational scientists, biologists, chemists and engineers. With the addition of Fez’s keen insights and business acumen for deals and partnerships, grounded in his medicinal chemistry background, we have the right mix of skills and perspectives on the leadership team that will help us bridge the gap between drug discovery and treatment.”

“I’m very excited to join the Terray team at this momentous stage,” said Dr. Ujjainwalla, “Having focused on cutting-edge biomedical technologies and strategic partnerships at Merck, I was immediately drawn to Terray’s sophisticated platform approach to developing quality chemical data at scale. Datasets like these, combined with the speed and power of machine learning, have the opportunity to open so many doors to research, collaborations, and transformative therapies.”

Dr. Ujjainwalla joins Terray from Merck, where he was most recently Director of Business Development and Licensing, having transitioned into Business Development after nearly two decades as a Medicinal Chemist. In 26 years of experience in small molecule drug discovery, he has led programs from inception to early clinical development, including the discovery of the first-in-class small molecule MC4R agonist, MK-0493, for the treatment of obesity. His licensing deals and strategic partnerships established numerous deals across a range of deal-types.

Dr. Ujjainwalla joins the following on the executive leadership team with Dr. Jacob Berlin, CEO, and Eli Berlin, Chief Financial and Operating Officer;

Dr. Vanessa Taylor, Head of Biology & Preclinical Development. Dr. Taylor joined Terray from Rigel Pharmaceuticals, where she led preclinical programs and was involved in taking seven drug candidates into clinical studies focused on inflammatory and rare diseases, and partnering of additional programs.

Dr. Narbe Mardirossian, Head of Computational and Data Sciences. A thought leader in quantum mechanics, machine learning, computational chemistry and closed-loop drug discovery, Dr. Mardirossian joined Terray from Amgen, where he supported computational small molecule drug discovery, including the development of advanced quantum mechanics and machine learning methods, as well as cloud-based solutions to support high-throughput, data-driven workflows.

Dr. Craig Schulz, Head of Automation. Dr. Schulz most recently was a Principal Scientist at Amgen responsible for designing, testing, and implementing automation solutions across Amgen’s discovery organization. He has invented numerous novel technologies that encompass enhancements to both small and large molecule synthesis, purification, and screening.

About Terray Therapeutics

Terray Therapeutics is an emerging biotechnology company led by pioneers and long-time leaders in AI, medicinal chemistry, biology and preclinical development, automation, and nanotechnology to propel drug discovery into the information age. Terray’s proprietary integrated computational and experimental platforms generate massively scaled, powerfully agnostic chemical data that are purpose-built to power computational learning and reveal new interactions. This foundation is building an iterative, flexible chemistry engine that aims to deliver more precise therapies to patients faster than ever before. Visit terraytx.com to learn more.

Media Contact:

Darby Pearson
dpearson@vergescientific.com

tNova platform leverages the world’s most dense and precise microarray to discover and develop transformative therapeutics

Series A Financing led by Madrona Venture Group with strong investor syndicate

PASADENA, Cali., February 15, 2022 – Terray Therapeutics, a biotechnology company propelling drug discovery into the information age, today announced the closing of a $60 million Series A financing to advance its novel tNova platform and deliver therapies to patients faster than ever before. The financing was led by Madrona Venture Group with participation from a broad syndicate of new and existing investors, including Two Sigma Ventures, Digitalis Ventures, KdT Ventures, Goldcrest Capital, XTX Ventures, Sahsen Ventures, Greentrail Capital and Alexandria Venture Investments. This financing follows a previously unannounced $20 million seed round co-led by Digitalis Ventures and Two Sigma Ventures.

“Even the most powerful artificial intelligence can’t get past insufficient or unclear data,” said Jacob Berlin, PhD, Chief Executive Officer of Terray. “Current chemical data lacks the scale and quality to enable AI-driven drug development. We’re building a future where the speed, precision and scale of our engine enable us to predictably create drugs that meet urgent patient needs.”

In today’s emerging frontier of AI-led drug discovery, Terray’s chemistry engine operates at an unrivaled scale, measuring billions of interactions daily and becoming increasingly precise with each cycle of design and experimentation. Chemical datasets generated using Terray’s novel ultra-dense microarray technology work seamlessly with Terray’s integrated machine learning and computational platform to systematically map biochemical interactions between small molecules and causes of disease. Combining these capabilities with unique resynthesis capabilities and broad biology infrastructure, Terray can answer an unprecedented array of questions to accurately navigate vast chemical space and deliver therapeutics for previously inaccessible targets.

“The right chemical data at scale is the only way to fuel a modern drug discovery engine. We’ve seen the impact that scaled data can deliver in other industries, and we are now leveraging that power and promise to deliver more precise therapies to patients faster than ever before,” said Eli Berlin, Chief Financial and Operating Officer of Terray.

Terray brings together a highly skilled, world-class team with deep pharma expertise and experience in AI, synthetic chemistry, biology, automation, and nanotechnology with the bold vision to harness the power of their discovery engine and put transformative therapeutics at our fingertips.

“Madrona is thrilled to support Terray’s mission of revolutionizing drug discovery and accelerating cures to patients,” said Chris Picardo, Partner at Madrona Venture Group. “We are excited by the Company’s world-class team of scientists and machine learning experts and the broad therapeutic potential of the tNova platform to drive solutions to our greatest medical problems.”

“Leveraging more than a decade of research from its founders, Terray has constructed a chemistry platform that systematically integrates high-throughput experimentation and computation at an unprecedented scale,” said Geoffrey W. Smith, Managing Partner of Digitalis Ventures. “This integration sets Terray apart by addressing a key industry pain point, generating clean and relatable data that enables AI-driven models to succeed in the highly complex space of chemical compounds,” added Dusan Perovic, Partner at Two Sigma Ventures.

The financing will be used to advance the Company’s preclinical pipeline of therapeutics and the Company’s discovery partnerships.

About Terray Therapeutics

Terray Therapeutics is an emerging biotechnology company led by pioneers and long-time leaders in AI, synthetic chemistry, automation, and nanotechnology to propel drug discovery into the information age. Terray’s proprietary integrated computational and experimental platforms generate massively scaled, powerfully agnostic chemical data that are purpose-built to power computational learning and reveal new interactions. This foundation is building an iterative, flexible chemistry engine that delivers more precise therapies to patients faster than ever before. Visit terraytx.com to learn more.

Media Contact:

Darby Pearson
dpearson@vergescientific.com