The Drug Discovery Engine Fueled by Premium Chemical Data

Our Approach

We generate chemical data purpose-built to revolutionize drug discovery. Through our closed-loop platform that combines wet lab discovery and data-rich AI, we derive breakthrough insights that lead to new drugs for patients in need.

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tArray: The Foundation of Our Discovery Engine

We rapidly synthesize and screen high diversity compound libraries to unlock chemical insights at an unrivaled scale. Hundreds of millions of compounds are measured in just minutes, returning the precise, quantitative data on each compound that powers our iterative approach.

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Our process starts by building massive combinatorial libraries on nanoparticle beads

Redundant DNA barcoding and solid phase synthesis allows us to use best-in-class chemistry for unmatched compound purity and diversity.

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The beads are immobilized in reusable chips the size of a nickel

DNA is sequenced in position, transforming chemical barcoding to spatial encoding.
The DNA tag is cleaved off, producing a DNA-free chip with thirty-two million compounds.

Binding affinity is measured by fluorescence

Chips are exposed to a target of interest and the precise binding affinity between every compound on a chip and the target is measured in less than five minutes.

tNova uses each cycle of tArray data to refine its AI models and determine which molecules should move forward

Powered by tArray’s iterative optimization, tNova evaluates the millions of compounds measured and trillions of related virtual molecules to prioritize compounds to progress.

tSynth and tBio: Testing and Refinement

Our automated tSynth platform rapidly resynthesizes prioritized compounds to provide the high purity, off-bead compounds necessary for tBio, our high throughput biological testing that measures biochemical and cell activity and in-vitro ADME.

tNova continually evolves by feeding data forward to power future library design and identification of molecules for progression
tLeads: From Technology to Therapy

The precise data provided at scale by tArray, tSynth and tBio, enables tNova to select final molecular refinements to be tested during medicinal chemistry optimization.

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With the world’s highest quality quantitative data at scale unlocking the power of AI-driven drug discovery, Terray is bringing drug discovery into the information age.
With the world’s highest quality quantitative data at scale
unlocking the power of AI-driven drug discovery, Terray is
bringing drug discovery into the information age.